Safety of Apixaban on pediatric heart disease on the prevention of embolism
People with certain types of heart disease may need to take medication to prevent their blood from clotting. That medication is called an anticoagulant or a blood thinner. The purpose of this study is to find out whether the medicine called Apixaban (commonly known as Eliquis®) is safe for children with heart disease, and to learn how much Apixaban will be present in the blood after taking a certain dose. Researchers will compare Apixaban to two other widely used blood thinners in children with congenital or acquired heart disease. Approximately 150 children will be enrolled over 36 months across 11 Pediatric Heart Network Centers and several centers in other countries.